BACKED BY DR. EMERAN MAYER
Feed Your Brain-Gut Connection
Seven of the most studied polyphenols in three daily capsules.
Shop Synaptic BloomSTART EATING FOR YOUR MICROBES
Your gut is home to trillions of living microbes
Through Dr. Mayer's decades of research, we've learned our gut microbes are responsible for digestion, immunity, and even brain function. They act to strengthen your gut ecosystem, enhance whole-body communication, and lay the foundation for longterm health.
90%
According to the CDC, more than 90% of Americans fall short of the recommended daily intake of fruits and vegetables, missing out on key dietary sources of polyphenols, which are essential for supporting the brain-gut-microbiome system and overall health.
1,000+
Human studies suggest that higher intakes of polyphenols (often above 1,000 mg/day) are associated with improved cardiovascular health, enhanced cognitive performance, and a more balanced gut microbiome. Yet, most people consume far less than this amount.
~100T
The gut is home to nearly 100 trillion microbes, an ecosystem shaped by diet and essential to brain, immune, and metabolic health. These microbes unlock the full potential of polyphenols by transforming them into bioactive compounds the body can absorb and use.
What Are Polyphenols?
Polyphenols are naturally occurring plant compounds concentrated in colorful fruits, vegetables, tea, and cocoa. While they’re often recognized for their antioxidant activity, human clinical studies show their benefits extend far beyond that.
Support brain health – Quercetin and other flavonoids have been shown in human trials to support memory, focus, and cognitive performance, particularly as we age. Certain compounds also improve blood flow to the brain and may reduce neuroinflammation.
Promote cardiovascular health – Quercetin supplementation in clinical studies has been linked to improved vascular relaxation, healthier blood pressure, and smoother circulation. Diets rich in polyphenols are consistently associated with a lower risk of heart disease.
Support gut health and microbial balance – Polyphenols interact with gut bacteria, encouraging the growth of beneficial species and enhancing production of short-chain fatty acids, which help maintain a resilient gut lining.
Together, polyphenols help optimize communication within the brain–gut–microbiome system, the body’s central network for long-term health and resilience.
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