





The Mayer Model (Signed Copy)
Optimize Your Health and Wellness with the Brain-Gut Connection
- By Emeran Mayer, MD, with Dylan Mayer, MS and Anu Simh, NBC-HWC
- 45 years of brain-gut research, made practical
- Seven pillars, one connected approach
- Includes a full chapter of gut-healthy recipes
Trillions of microbes in your gut are in constant conversation with your brain. What you eat, how you move, how you sleep and how you handle stress all shape that conversation.
In The Mayer Model, Dr. Emeran Mayer draws on 45 years of research at UCLA to show that lasting wellbeing comes from seven connected pillars: food, exercise, mindfulness, resilience, sleep, community and purpose. Written with Dylan Mayer, MS, and Board Certified Health Coach Anu Simh, it turns that science into practical, evidence-based guidance for real people on real days.
It's not a book about restriction. It's about restoring balance in a way that lasts.
Signed copies ship from Mayer Nutrition. Amazon copies are sold and shipped by Amazon.

From the back cover
“This book is for the person who has been doing everything ‘right’ and still does not feel well.”

Emeran Mayer, MD
Inside The Mayer Model
Forty-five years of research on how the brain, gut and microbiome talk to each other, organized into a framework you can actually use. Each chapter moves from the science to what to do with it.
- Authors
- Emeran Mayer, MD
- With Dylan Mayer, MS and Anu Simh, NBC-HWC
- Format
- Hardcover
- Chapters
- 7
- From brain-gut science to daily practice
- Includes
- Recipes
- Plus movement, sleep and mindfulness practices
- ISBN
- 979-8-234-12066-3
Written for general readers. No science background needed.
The Seven Pillars
Lasting wellbeing isn’t the product of one good habit. The Mayer Model is built around seven connected pillars, each with its own role in supporting the brain-gut-microbiome system.
They don’t work in isolation. Improving one tends to lift the others, which is why the book treats them as one system rather than a checklist.

Food
Plant-rich, fiber-forward, polyphenol-dense eating, fitted to you rather than a rigid plan.
Exercise
Regular movement, one of the most powerful tools for keeping the brain-gut system working well.
Mindfulness
Meditation, breathwork and present-moment awareness to calm the stress response.
Resilience
Ways of handling life’s stress that support, rather than strain, the gut.
Sleep
The hours when the brain and gut do their most restorative work.
Community
Shared meals and real connection, which benefit the brain and gut alike.
Purpose
A sense of meaning that makes healthy habits easier to keep.

Committed to Science, Not Trends
Wellness has been overtaken by influencers and self-proclaimed gurus, most of them working without a scientific foundation. Meanwhile the real research on the brain-gut connection, polyphenols, and the microbiome sits locked in academic journals where almost no one reads it.
Mayer Nutrition exists to close that gap. Founded by Dr. Emeran Mayer, a gastroenterologist and neuroscientist who has spent his career studying the links between the gut, brain, and microbiome, alongside Dylan Mayer, MS, whose background is in neuroscience, nutrition, and human performance.
Every product is research-driven, built on ingredient integrity, and transparent by design. You should know exactly what you are putting in your body.
Inside the Chapters

Food as Daily Medicine
The Mediterranean diet, fiber, polyphenols and naturally fermented foods, and why each one matters to your microbes.

Gut-Healthy Recipes
A full chapter of simple dishes built on the book’s food principles, with tips on how to prepare them.

Building a Gut-Healthy Lifestyle
Movement, sleep, mindfulness and vagus nerve practices that bring the seven pillars into everyday life.
Frequently Asked Questions
The questions we get most, answered properly.
Who is this book for?
Anyone who wants to understand how the brain, gut and microbiome work together, and turn that into daily habits. As the back cover puts it, it’s for the person who has been doing everything “right” and still does not feel well. No science background needed.
Are copies signed?
Signed copies available while supplies last.
How is it different from The Mind-Gut Connection?
The Mind-Gut Connection explains the science of how the brain and gut communicate. The Mayer Model builds on that research and focuses on what to do with it: a framework of seven pillars, with practical guidance on food, movement, sleep, mindfulness and more.
Does it include recipes?
Yes. Chapter 6 is a full chapter of gut-healthy recipes by Anu Simh, NBC-HWC, built around the book’s food principles. For more Mediterranean dishes, see Dr. Mayer’s cookbook, Interconnected Plates.
How fast will I get it, and what if something is wrong?
Orders are processed within 1 to 2 business days and you will get tracking as soon as it ships. Standard delivery runs 3 to 7 business days, with expedited options available at checkout. We ship worldwide.
If your book arrives damaged, or if it is marked delivered and never shows up, email hello@mayernutrition.com within 7 days and we will sort it out. Same if you receive the wrong item. Include your order number and a photo if you have one.